The CRMP-2 (Ab-509) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CRMP2, DPYSL2, and TOAD-64. This antibody recognizes Human antigen. The CRMP-2 (Ab-509) Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.Goshima Y., Nature 376:509-514(1995).Hamajima N., Gene 180:157-163(1996).Kitamura K., DNA Res. 6:291-297(1999)